General Cell Based Assays
Eurofins Discoverx PathHunter Human Calcitonin (CALCR (No RAMP)) β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human Calcitonin (CALCR (No RAMP)) β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure CALCR (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx cAMP Hunter™ Human ADCYAP1R1 (PAC1) Cell-Based Assay Kit (CHO-K1)
The cAMP Hunter™ Human ADCYAP1R1 (PAC1) Gs Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure ADCYAP1R1 (GPCR) activity via increased levels of intracellular cAMP. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter eXpress mCNR2 CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0472E2MCP0L)
The PathHunter mCNR2 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. CP 55,940) based activation of mCNR2 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mCNR2 and EA-tagged β-Arrestin-2. Activation of mCNR2 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Medchemexpress LLC cGAS Human His-SUM 10ug
Recombinant human cyclic GMP-AMP synthase (cGAS) fragment G161-F522, expressed in E. coli and supplied lyophilized with an N-terminal 6xHis-SUMO tag. The protein is purified to >90% and provided with storage and reconstitution guidance to preserve activity for biochemical and structural applications.
- Recombinant human cGAS fragment G161-F522 with N-terminal His-SUMO tag.
- Expressed in E. coli and purified to greater than 90% purity.
- Lyophilized formulation for improved stability and convenient storage.
- Buffer contains trehalose to protect protein during lyophilization.
- Suitable for biochemical assays, enzymatic activity, and structural studies.
- Includes storage and reconstitution guidance to maintain activity.
Eurofins Discoverx PathHunter OSMRb/IL31R Bioassay Kit, 2-Plate. (93-1002Y3-00083)
The PathHunter OSMRb/IL31R Dimerization Bioassay kit provides an easy-to-use cell based assay to measure drug potency and detect neutralizing antibodies. This bioassay assesses ligand (e.g. IL-31) induced dimerization of OSMRb/IL31R receptors. This product uses EFC technology. The cell line included overexpresses OSMRb target protein fused to PK alongside IL31RA target protein fused to EA. Upon ligand-induced dimerization of OSMRb/IL31R, detectable EFC signal is produced. Bioassay kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, control agonist, detection reagent, and assay plates. For detailed product information, User manual and COA, visit www.discoverx.com/bioassay.
Eurofins Discoverx PathHunter Human VEGF (KDR/KDR) Dimerization Cell-Based Assay Kit (HEK 293)
The PathHunter Human VEGF (KDR/KDR) Stable Cell Line Dimerization Assay (HEK 293) measures ligand-induced dimerization of KDR/KDR. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Meso Scale Discovery R-PLEX Human AFP ASY
The R-PLEX Human AFP Assay from Meso Scale Diagnostics is an electrochemiluminescent immunoassay for the quantitative measurement of alpha-fetoprotein (AFP) in human serum plasma and tissue culture supernatant This assay utilizes MSD s proprietary SULFO-TAG labels and multi-array technology to provide a highly sensitive and reproducible method for detecting AFP an important biomarker used to help diagnose and monitor hepatocellular carcinoma and other malignancies as well as fetal defects The assay has a wide dynamic range of 1 95-2000 pg/mL and requires only 50 L of sample
Brookfield Engineer Labs VIAL TESTING ASSAY KIT 10PK
DescriptionGlass Sample bottles with metal cap and septa. Compatible with Vapor Pro instruments CT-3100(-L) and CT-4200XL. Includes 10 glass sample bottles.
Sigma Aldrich Fine Chemicals Biosciences Heme Assay Kit sufficient
Heme is a member of the porphyrin family. It is synthesized in both mitochondria and cytoplasm and is a key prosthetic group for various essential proteins such as hemoglobin cytochromes catalases and peroxidases. free heme which can be released from hemoglobin following hemolysis is pro-inflammatory and contributes to iron-derived reactive oxygen species. Heme determination is widely practiced by researchers of various blood diseases.
Abcam SIRT2 Activity Assay Kit (Fluorometric)
SIRT2 Activity Assay Kit (Fluorometric)
The product is subject to the following: Abcam Restricted Use Statement
Eurofins Discoverx PathHunter eXpress TYK2 Activity Assay, 2-Plate Kit. (93-0875E3CP16M)
The PathHunter eXpress TYK2 Activity Assay is a stable, engineered cell line for use in studying small molecule drug candidates targeting the TYK kinase domain. The cell line is engineered to express the catalytic domain from TYK2 fused to the cytokine receptor binding domain (CRBD) of JAK2. The cells co-express an Enzyme Acceptor (EA) tagged SH2 domain and a ProLink (PK) tagged Cytokine receptor. The CRBD is designed to bind the CTK catalytic domain to the GHR-PK. Activation of the GHR-PK induces receptor phosphorylation by the TYK2 catalytic domain. This leads to SH2-EA recruitment and production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter IL17RA/IL17RC Dimerization Bioassay Kit, 2pl. (93-0999Y3-00053)
The PathHunter IL17RA/IL17RC Dimerization Bioassay kit provides an easy-to-use cell based assay to measure drug potency and detect neutralizing antibodies. This bioassay assesses ligand (e.g. IL-17) induced dimerization of IL17RA/IL17RC receptors. This product uses EFC technology. The cell line included overexpresses IL17RC target protein fused to PK alongside IL17RA target protein fused to EA. Upon ligand-induced dimerization of IL17RA/IL17RC, detectable EFC signal is produced. Bioassay kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, control agonist, detection reagent, and assay plates. For detailed product information, User manual and COA, visit www.discoverx.com/bioassay.
Meso Scale Discovery R-PLEX Rat IL-2 ASY
The R-PLEX Rat IL-2 Assay Kit from Meso Scale Discovery measures rat interleukin 2 (IL-2) in various biological fluids using MSD s electrochemiluminescent detection technology It offers high sensitivity a wide dynamic range and low sample volume requirements The kit includes a 96-well plate with capture antibodies detection antibodies calibrators and necessary reagents Results are available in 3 5 hours using an MSD instrument This assay quantitatively measures rat IL-2 crucial for the immune system
STEMCELL Technologies Cell NavigatorTM Golgi Stain
Kit containing C6 NBD ceramide for selectively staining the Golgi apparatus in live or aldehyde-fixed cells - 100 Tests
American Research Products Inc Myc (Phospho-Thr58) Transcription Factor Activity Assay
Myc (Phospho-Thr58) Transcription Factor Activity Assay